Circ_0000285 promotes podocyte injury through sponging miR-654-3p and activating MAPK6 in diabetic nephropathy.

Gene(2020)

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摘要
•Circ_0000285 was elevated while miR-654-3p was down-regulated in DN.•Circ_0000285 acted as a sponge of miR-654-3p.•MAPK6 functioned as downstream target of miR-654-3p.
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关键词
circRNAs,DN,EdU,ELISA,CCK-8,QRT-PCR,cDNA,IL-6,TNF-α,IL-1β,MAPK,NC
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