Role of apolipoprotein E in electronegative low-density lipoprotein-induced mitochondrial dysfunction in cardiomyocytes.

Wei-Yu Chen,Yun-Fang Chen, Hua-Cheng Chan,Ching-Hu Chung,Hsien-Yu Peng,Yu-Cheng Ho,Chu-Huang Chen,Kuan-Cheng Chang,Chih-Hsin Tang,An-Sheng Lee

Metabolism（2020）

引用 13|浏览23

暂无评分

摘要

•Electronegative LDL (L5) induced dysfunction of mitochondrial energy production.•ApoE was released and colocalized with VDAC after L5 was taken up by myocytes.•Recombinant ApoE mimicked the effect of L5 on cardiomyocytes.

查看译文

关键词

Apo,ApoE,CaMKII,DIPE,Drp1,FCCP,HDL,LDL,LOX-1,LRP1,mPTP,OCR,oxLDL,PCSK9,SDS,SRC,VDAC,VLDL

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要