A pharmacodynamic model of clinical synergy in multiple myeloma.

Praneeth Sudalagunta,Maria C Silva,Rafael R Canevarolo,Raghunandan Reddy Alugubelli,Gabriel DeAvila,Alexandre Tungesvik,Lia Perez,Robert Gatenby,Robert Gillies,Rachid Baz,Mark B Meads,Kenneth H Shain,Ariosto S Silva

EBioMedicine（2020）

引用 18|浏览74

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摘要

This research was funded by the H. Lee Moffitt Cancer Center Physical Sciences in Oncology (PSOC) Grant (1U54CA193489-01A1) and by H. Lee Moffitt Cancer Center's Team Science Grant. This work has been supported in part by the PSOC Pilot Project Award (5U54CA193489-04), the Translational Research Core Facility at the H. Lee Moffitt Cancer Center & Research Institute, an NCI-designated Comprehensive Cancer Center (P30-CA076292), the Pentecost Family Foundation, and Miles for Moffitt Foundation.

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关键词

Clinical synergy,Multiple myeloma,Ex vivo,Pharmacodynamic model,High-throughput combination screening

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