DNA damage, repair and the improvement of cancer therapy - A tribute to the life and research of Barbara Tudek.

Agnieszka Tudek,Jolanta Czerwińska,Konrad Kosicki,Daria Zdżalik-Bielecka,Somayeh Shahmoradi Ghahe,Milena Bażlekowa-Karaban, Ewelina M Borsuk,Elżbieta Speina

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2020）

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摘要

•The manuscript is dedicated to Barbara Tudek, EEMGS FH Sobels Award 2019 Winner.•Repair of 8-OxoGua and etheno adducts may serve as cancer progression markers.•Oxidized PUFAs contribute to cancer development and accelerate aging.•A nano-emulsion drug delivery system and PDT may support anti-cancer therapy.

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关键词

FapyGua,Fapy-7MeGua,FapyAde,Fapy-7MeAde,8-oxoGua,εAde,εdA,εCyt,εdC,1N2-εGua,1N2-εdG,ICL,ROS,LPO,HNE,CRO,ACR,AD,CRC,XRCC1,APE1,BER,NER,NIR,TLS,PDT

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