Placebo and nocebo effects for itch and itch-related immune outcomes: A systematic review of animal and human studies

Stefanie H. Meeuwis,Henriët van Middendorp,Antoinette I.M. van Laarhoven, Cora van Leijenhorst,Gustavo Pacheco-Lopez,Adriana P.M. Lavrijsen,Dieuwke S. Veldhuijzen,Andrea W.M. Evers

Neuroscience & Biobehavioral Reviews（2020）

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摘要

•Social, instructional and associative learning can induce placebo effects.•These same mechanisms can underlie nocebo (or negative) effects.•Placebo and nocebo effects can influence itch and itch-related immune outcomes.•Brain areas responsible for processing of itch are associated with nocebo effects in itch.•Placebo effects may be used to improve clinical symptoms and conditions of the skin.

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关键词

Placebo effects,Nocebo effects,Itch,Dermatology,Conditioning,Expectancy

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