The role of complement activation in autoimmune liver disease

Maaike Biewenga,Arantza Farina Sarasqueta,Maarten E. Tushuizen,Eveline S.M. de Jonge-Muller,Bart van Hoek,Leendert A. Trouw

Autoimmunity Reviews（2020）

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摘要

•Complement has an important role in the pathophysiology of many autoimmune diseases.•Knowledge about the role of complement in autoimmune liver disease is limited.•In autoimmune hepatitis increased levels of IgG and autoantibodies are present.•On histology no complement deposition was found in autoimmune liver disease.•The role of complement in autoimmune liver disease seems limited.

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关键词

Autoimmune hepatitis,Primary biliary cholangitis,Primary sclerosing cholangitis,Complement activation

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