Dietary Luffa cylindrica (L.) Roem promotes branched-chain amino acid catabolism in the circulation system via gut microbiota in diet-induced obese mice

Lu Zhang,Yunshuang Yue,Mengxuan Shi,Meiling Tian,Junfu Ji,Xiaojun Liao,Xiaosong Hu,Fang Chen

Food Chemistry（2020）

引用 31|浏览22

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摘要

•BCAAs can be regarded as serum biomarkers for obesity.•Luffa potentially suppressed bacterial BCAA biosynthesis.•Luffa-affected bacterial metabolites triggered tissue-specific BCAA catabolism.•Luffa improved circulating BCAA dysfunction via gut microbiota to attenuate obesity.

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关键词

ALT,AN,AST,AUC,BCAA,BCATm,BCKA,BCKDK,BMI,DIO,FSG,FSI,HE,HOMA-IR,HFD,IGTT,Ile,IR,ITT,KEGG,Leu,LEfSe,Luffa cylindrica (L.)Roem,MRM,NCD,NMR,OTU,PAS,PCoA,PERMANOVA,PICRUSt,RDA,SCFA,SPF,TC,TG,Val

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