Development of a DNA Adductome Mass Spectral Database.

Jingshu Guo,Robert J Turesky,Anamary Tarifa,Anthony P DeCaprio,Marcus S Cooke,Scott J Walmsley,Peter W Villalta

CHEMICAL RESEARCH IN TOXICOLOGY（2020）

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摘要

Mass spectrometry-based DNA adductomics is an emerging approach for the human biomonitoring of hazardous chemicals. A mass spectral database of DNA adducts will be created for the scientific community to investigate the associations between chemical exposures, DNA damage, and disease risk.

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