Corrigendum to "A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm" [Toxicology and Applied Pharmacology volume 394C (2020) 114961].

•hERG potency/safety margin is a widely used nonclinical cardiac safety strategy.•A new regulatory paradigm promotes the integration of nonclinical and clinical data.•Lack of uncertainty quantification hindered using hERG potency in the new paradigm.•A systematic method was established to address this limitation.•Analysis supports using different safety margin thresholds in different context.