Comparative Ligandomic Analysis of Human Lung Epithelial Cells Exposed to PM2.5

These results suggest that the newly-developed ligandomics is a valuable approach to globally profile the response of LECs to PM in terms of regulating the expression of cell surface receptors, as quantified by ligand binding activity. This quantitative ligandome profiling will provide in-depth understanding of the LEC molecular response on the cell surface to particulate matter air pollution.