Generating Electronic Health Records with Multiple Data Types and Constraints

Sharing electronic health records (EHRs) on a large scale may lead to privacy intrusions. Recent research has shown that risks may be mitigated by simulating EHRs through generative adversarial network (GAN) frameworks. Yet the methods developed to date are limited because they 1) focus on generating data of a single type (e.g., diagnosis codes), neglecting other data types (e.g., demographics, procedures or vital signs) and 2) do not represent constraints between features. In this paper, we introduce a method to simulate EHRs composed of multiple data types by 1) refining the GAN model, 2) accounting for feature constraints, and 3) incorporating utility measures for such generation tasks. The findings over 770K EHRs from Vanderbilt University Medical Center demonstrate that our model achieved higher data utilities in retaining the basic statistics, interdimensional correlation, structural properties and frequent association rules from real data. Importantly, these were done without sacrificing privacy.