Pneumocystis Pneumonia And Acute Kidney Injury Induced By Everolimus Treatment In A Patient With Metastatic Breast Cancer
CASE REPORTS IN ONCOLOGY(2020)
摘要
Everolimus, an inhibitor of the rapamycin pathway, is administered with the combination of an aromatase inhibitor for the treatment of metastatic estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancers. Interstitial lung disease is a well-known major adverse event associated with everolimus treatment, but it is often difficult to distinguish between interstitial lung disease and Pneumocystis pneumonia, a lung infection. Acute kidney injury is another adverse event that is associated with everolimus use. In this article, we report a case of Pneumocystis pneumonia without respiratory symptoms and acute kidney injury induced by everolimus treatment in a patient with ER-positive and HER2-negative metastatic breast cancer.
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关键词
Pneumocystis pneumonia, Acute kidney injury, Everolimus, Breast cancer
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