A Phase IB study of Durvalumab with or without Tremelimumab and Platinum-Doublet Chemotherapy in Advanced Solid Tumours: Canadian Cancer Trials Group Study IND226

Lung Cancer(2020)

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摘要
•Durvalumab and tremelimumab can be safely given with platinum-doublet chemotherapy.•Tremelimumab and durvalumab exposures did not appear affected by chemotherapy.•Efficacy in NSCLC is comparable to other immunotherapy/chemotherapy trials.
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关键词
Durvalumab,Tremelimumab,Phase I,Immunotherapy,Lung cancer
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