Perinatal thalamic injury: MRI predictors of electrical status epilepticus in sleep and long-term neurodevelopment

•The majority of patients with perinatal thalamic injury, will develop epilepsy with ESES after the age of two years.•ESES is associated with neurodevelopmental deficits.•Larger residual thalamic volume at the three months MRI correlates to higher total IQ/DQ during follow-up.•MRI at three months appears to be useful to predict neurodevelopmental outcome in this population.