Novel Rapid Test for Detecting Carbapenemase

Yanfang Feng,Akilan Palanisami,Jerrin Kuriakose,Michael Pigula,Shoaib Ashraf,Tayyaba Hasan

EMERGING INFECTIOUS DISEASES（2020）

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摘要

We developed a carbapenemase test based on the ability of imipenem to inhibit noncarbapenemase beta-lactamases. The test uses bacterial isolates with a fluorescent beta-lactamase substrate, producing objective results with 100% sensitivity and specificity in 10 minutes. The assay is inexpensive and consists of only 1 mixing step.

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关键词

Laboratory diagnosis,bacteria,carbapenemase,fluorescence,gram-negative bacteria,rapid test

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