3.5 Arterial Stiffness Partly Explains Sex Differences in Associations Between Left Ventricular Structure and Mortality: The Southall and Brent Revisited (SABRE) Study

We have previously shown that 3D echocardiography-derived (3DE) indices of left ventricular (LV) structure predict all-cause mortality differently in men and women [1]. However, the mechanism behind these sex differences remains unknown. We therefore examined the role of macro- and micro-vascular disease in explaining these sex differences. 910 individuals (age, 69.7 ± 6.2 years; 77.7