The impact of hidradenitis suppurativa on general health is higher than that of hypertension, congestive heart failure, type 2 diabetes, myocardial infarction, and depression.

Quality of life (QoL) in patients with hidradenitis suppurativa (HS) is severely impaired . Such impairment may exceed that of other burdensome skin diseases, such as psoriasis, neurofibromatosis 1, chronic urticaria, and atopic dermatitis . It was recently shown , reviewing data from different studies, that the impact of HS was comparable to that of cardiovascular diseases, chronic obstructive pulmonary disease, or diabetes mellitus.