Tumor microenvironment: Challenges and opportunities in targeting metastasis of triple negative breast cancer

K.G.K. Deepak, Rahul Vempati,Ganji Purnachandra Nagaraju,Venkata Ramesh Dasari,S. Nagini,D.N. Rao,Rama Rao Malla

Pharmacological Research（2020）

引用 238|浏览5

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摘要

•TNBC is highly challenging subtype of breast cancer due to unique tumor microenvironment (TME).•TME associates with aggressive nature, metastasis and drug resistance in TNBC.•Epigenetic based regulations within TME drive carcinogenesis.•Novel therapeutic targets of TME helps in early diagnosis and effective treatment of TNBC.

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关键词

Chemoresistance,Metastasis,Phytochemicals,Tumor microenvironment and TNBC

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