Molecular regulatory network of PD-1/PD-L1 in non-small cell lung cancer

Zhu Lingling,Liu Jiewei,Wang Li,Yan Danli,Zhou Jie,Li Wen,Pu Dan, Peng Lei,Zhou Qinghua

Pathology - Research and Practice（2020）

引用 11|浏览19

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摘要

•Non-small cell lung cancer (NSCLC) is the major pathologic subtype of lung cancer.•Four immunotherapy drugs targeting PD-1/PD-L1 checkpoints are used to treat NSCLC.•The mechanisms of PD-L1 regulation are not clearly understood.•This review provides an overview of recent updates on PD-L1 regulation.

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关键词

Immunotherapy,Non-Small cell lung cancer,Programmed death ligand 1

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