Antibody Blockade Of Semaphorin 4d To Sensitize Pancreatic Cancer To Immune Checkpoint Blockade

Luis I. Ruffolo,Nicholas A. Ullman,Benjamin Dale,Katherine M. Jackson,Paul Burchard,Mary Georger,Rachel Jewell,Brian A. Belt,Eva Galka,Luke O. Schoeniger,Crystal L. Mallow,Elizabeth E. Evans,Terrence Lee Fisher,Maurice Zauderer,David Linehan

JOURNAL OF CLINICAL ONCOLOGY（2020）

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26Background: Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis, and will soon become the second leading cause of cancer mortality. Unfortunately, T-cell directed immunotherapies h...

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