Multi-Institutional, Prospective, Randomized, Double-Blind, Placebo-Controlled Phase Iib Trial Of The Tumor Lysate, Particle-Loaded, Dendritic Cell (Tlpldc) Vaccine To Prevent Recurrence In High-Risk Melanoma Patients: A Subgroup Analysis

JOURNAL OF CLINICAL ONCOLOGY(2020)

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摘要
The TLPLDC vaccine improved DFS in patients completing the primary vaccine series, particularly in the resected stage IV patients. The efficacy of the TLPLDC vaccine will be confirmed in a phase III study evaluating adjuvant TLPLDC + CPI versus Placebo + CPI in resected stage IV melanoma patients.
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关键词
cancer vaccine,immunotherapy,melanoma,personalized medicine
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