5-hydroxymethylation signatures in plasma circulating cell-free DNA as markers for appendiceal and colorectal peritoneal metastasis.

Yaniv Berger,Xiao-Long Cui,Diana West,Marco Rivas,Phillip Hsu,Urszula Dougherty,Zifeng Deng,Enal Hindi,Oliver Eng,Marc Bissonnette,Blase N. Polite,Kiran Turaga

ANNALS OF SURGICAL ONCOLOGY（2020）

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摘要

195Background: Noninvasive tests for peritoneal metastasis (PM) detection lack sensitivity. Genome-wide mapping of 5-hydroxymethylcytosine (5hmC) on nanogram quantities of peripheral plasma circula...

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