Impaired activation of Notch-1 signaling hinders repair processes of bronchial epithelial cells exposed to cigarette smoke.

C Di Sano, C D'Anna,M Ferraro,G Chiappara,C Sangiorgi,S Di Vincenzo,A Bertani,P Vitulo,A Bruno,P Dino,E Pace

Toxicology Letters（2020）

引用 10|浏览32

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摘要

•Notch-1 intervenes in the reparative processes of the airway mucosa.•cigarette smoke exposure limits Notch-1 signaling activation in bronchial epithelial cells.•cigarette smoke exposure hinders repair processes in bronchial epithelial cells.

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关键词

CS,CSE,Notch-1,Jag-1,IL-33,DAPT

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