Correspondence on: 'Dupilumab as a novel steroid-sparing treatment for IgG(4)-related disease' by Simpson et al

ANNALS OF THE RHEUMATIC DISEASES(2022)

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We thank Ebbo et al for their interest in our case report1 and for providing their case of a patient with IgG4-related disease (IgG4-RD) whom they have also treated with dupilumab.2 Notably, Ebbo et al reported variability in the response to dupilumab compared with our patient. Our patient did have different clinical manifestations than that of Ebbo et al ’s patient, as our patient had profound retroperitoneal and genitourinary fibrosis along with atopic dermatitis, asthma, allergic rhinoconjunctivitis, parotitis, and sinusitis while Ebbo et al ’s patient presented with dacryoadenitis and sialadenitis in conjunction with allergic manifestations such as chronic rhinosinusitis with nasal polyps, asthma and urticaria. We are curious also to ask if the relationships between the variables presented in Figures C, D and …
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DMARDs (biologic),inflammation,T Cells
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