Clinical-genomic Characterization Unveils More Aggressive Disease Features in Elderly Prostate Cancer Patients with Low-grade Disease

Hanan Goldberg,Daniel Spratt,Thenappan Chandrasekar,Zachary Klaassen,Christopher J D Wallis,Maria Santiago-Jimenez,Nick Fishbane,Elai Davicioni,Rodrigo Noorani,Ardalan E Ahmad,Jaime Omar Herrera Cáceres,Shabbir Alibhai,Alejandro Berlin,Neil Eric Fleshner

European Urology Focus（2021）

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摘要

Using genomic classifier scores, older men with low-risk prostate cancer were shown to harbor more aggressive disease than younger patients. This suggests that elderly patients with presumed-indolent disease may harbor a more aggressive phenotype, possibly requiring more active treatment.

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关键词

Age,Decipher,Genomic classifier,Gleason group grade,Prostate cancer

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