Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells.

Ryunosuke Kitajima,Risako Nakai,Takuya Imamura,Tomonori Kameda,Daiki Kozuka,Hirohisa Hirai,Haruka Ito,Hiroo Imai,Masanori Imamura

Stem Cell Research（2020）

引用 5|浏览16

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摘要

•Generation and maintenance of chimpanzee iPSCs under feeder-free culture.•Rapid and efficient induction of NSCs from iPSCs by direct neurosphere formation.•Sequential early neural development during neurosphere formation.

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关键词

Chimpanzee,iPSCs,In vitro differentiation,Neural development

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