68 Consecutive patients assessed for COVID-19 infection; experience from a UK regional infectious disease unit
medRxiv(2020)
摘要
Clinical assessment of possible infection with SARS-CoV-2, the novel coronavirus responsible for the
outbreak of COVID-19 respiratory illness, has been a major activity of infectious diseases services in
the UK and elsewhere since the first report of cases in December 2019. We report our case series of
68 patients, reviewed by Infectious Diseases Consultants at a Regional Infectious Diseases Unit in the
UK. We prospectively evaluated our service between the 29th Jan 2020 and 24th Feb 2020.
Demographic, clinical, epidemiological and laboratory data were collected. We have compared
clinical features and subsequent diagnosis between well patients not requiring admission for clinical
reasons or antimicrobials with those assessed as needing either admission or antimicrobial
treatment.
Final microbiological diagnoses included SARS-CoV-2 (COVID-19), Mycoplasma pneumonia, influenza
A, RSV, non SARS/MERS coronaviruses, rhinovirus/enterovirus. 9/68 were treated with
antimicrobials, 15/68 were admitted to a negative pressure room of whom 5/68 were admitted
solely due to an inability to isolate at home. Patients requiring either admission on clinical grounds
or antimicrobials (14/68) were similar to those not requiring admission or antimicrobials, with
modestly more fever and shortness of breath in the clinically admitted / antimicrobial group. The
most commonly prescribed antimicrobials were doxycycline, moxifloxacin and oseltamivir.
The majority of patients had mild illness which did not require a clinical intervention to manage. This
finding supports a community testing approach supported by clinicians to review the proportion of
more unwell patients.
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关键词
COVID-19,Community assessment,Respiratory infection,SARS-CoV-2
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