Management of patients with acute lymphoblastic leukemia in routine clinical practice: Minimal residual disease testing, treatment patterns and clinical outcomes in Belgium, Greece and Switzerland
Leukemia Research(2020)
摘要
•ALL is associated with considerable clinical and economic burden.•Median OS was 28.9 months, 76 % of patients were hospitalized (mean 1.1 time/month).•MRD+ patients have worse prognosis than MRD- patients.•Median OS for MRD+ patients was 15.3 months; MRD-: not reached.•Efforts should be made to adhere to recommendations for MRD testing in clinical guidelines.
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关键词
AE,ALL,ALLIC-BFM,AYA,CI,CRh,ECOG,GMALL,GRAALL,HCRU,HOVON,HyperCVAD,LOS,MRD,NOS,NR,OS,PCR,RFS,SD,SCT
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