H3K9 Demethylation-Induced R-Loop Accumulation Is Linked to Disorganized NucleoliWOS
Frontiers in genetics, pp. 432020.
Keywords:H3K9 dimethylationR-loopsmultiple nucleoliribosomal DNAtranscription inhibition
The nucleolar structure and integrity are important for a range of cellular functions of the nucleoli. It has been shown that cells lacking histone H3 Lysine 9 (H3K9) methylation form fragmented nucleoli. However, the molecular mechanism involved remains poorly understood. Here, we present evidence suggesting that loss of H3K9 dimethylati...More