H3K9 Demethylation-Induced R-Loop Accumulation Is Linked to Disorganized NucleoliWOS

    Hong Zhou
    Hong Zhou
    Le Li
    Le Li
    Qing Wang
    Qing Wang
    Yan Hu
    Yan Hu
    Weiwei Zhao
    Weiwei Zhao
    Mayank Gautam
    Mayank Gautam
    Cited by: 0|Bibtex|13|

    Frontiers in genetics, pp. 432020.

    Keywords:
    H3K9 dimethylationR-loopsmultiple nucleoliribosomal DNAtranscription inhibition

    Abstract:

    The nucleolar structure and integrity are important for a range of cellular functions of the nucleoli. It has been shown that cells lacking histone H3 Lysine 9 (H3K9) methylation form fragmented nucleoli. However, the molecular mechanism involved remains poorly understood. Here, we present evidence suggesting that loss of H3K9 dimethylati...More
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