The prognostic value of volumetric changes of the primary tumor measured on Cone Beam-CT during radiotherapy for concurrent chemoradiation in NSCLC patients.

Margriet Kwint,Barbara Stam,Cécile Proust-Lima,Viviane Philipps,Trynke Hoekstra,Else Aalbersberg,Maddalena Rossi,Jan-Jakob Sonke,José Belderbos,Iris Walraven

Radiotherapy and Oncology（2020）

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摘要

•394 LA-NSCLC patients treated with concurrent chemoradiotherapy.•GTV-change during treatment was analyzed with Latent Class Mixed Modelling.•Three different subgroup of GTV-change during chemoradiation treatment.•Baseline GTV significantly associated with overall survival.

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关键词

Cone-Beam-CT,Concurrent chemoradiation,Locally Advanced NSCLC,Volumetric changes,Latent Class Mixed Modelling

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