Organosilanes In The Synthesis Of Saturated Heterocycles

This account summarizes the studies towards the synthesis of saturated heterocycles using the chemistry of organosilanes. Two different synthetic approaches are described: a) the acid-mediated cyclization of unsaturated silyl alcohols and b) the silyl-Prins (or silyl-aza-Prins) cyclization of silylated alkenols. The effect of substitution on the selectivity of the annulation process is evaluated.[GRAPHICS].