Mechanisms of resistance to mTOR inhibitors
Critical Reviews in Oncology/Hematology(2020)
摘要
•PI3K/AKT/mTOR pathway is disrupted in multiple tumor types.•Several class of mTOR inhibitors exist, with different mechanisms of resistance.•It is crucial to identify factors predictive/prognostic of response/resistance.•Predictive factors may help to select patients benefiting from a specific agent.•Novel and different mechanisms of resistance are still under investigation.
更多查看译文
关键词
mTOR inhibitors,Mechanisms of resistance,Predictive factors
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要