Highly Sensitive and Selective Detection of Human-Derived Volatile Organic Compounds Based on Odorant Binding Proteins Functionalized Silicon Nanowire Array

•The real-time, ultrasensitive, reproducible detection of VOCs based on free-standing SiNW-AgOBP device was reported.•The sensor possessed high sensitivity down to several ppb, and outstanding selectivity.•The device showed reproducible and long-lasting performances.