Synthesis, Characterization and Anti-HIV Activity of Polycarboxylic [60]Fullerene Derivatives Obtained in the Reaction of C60Cl6 with a Hydroquinone Ether

Ilya I. Voronov,Vyacheslav M. Martynenko,Alexander V. Chernyak,Ivan Godovikov,Alexander S. Peregudov,Jan Balzarini,Alexander F. Shestakov,Dominique Schols,Pavel A. Troshin

Tetrahedron Letters（2020）

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摘要

•Reaction of C60Cl6 with p-hydroquinone ether gives five products with untypical structures.•Molecular structures of novel compounds confirmed by APCI-MS and NMR spectroscopy.•Isolated compounds demonstrated potent activity against R5 and X4 HIV-1 strains.

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关键词

Water-soluble fullerene derivatives,Anti-HIV activity,HIV tropism,Benzofurane-type structure

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