Left ventricular wall thickness measured with computed tomography predicts clinical outcomes in patients receiving cardiac resynchronization therapy

Abstract Background Up to 30% of selected heart failure patients do not benefit clinically from cardiac resynchronization therapy (CRT). Left ventricular (LV) wall thickness (WT) analyzed using computed tomography (CT) has rarely been evaluated in response to CRT and mitral regurgitation (MR) improvement. Purpose We examined the association of LVWT and the ability for reverse LV remodeling and MR improvement after CRT. Methods Fifty-four patients scheduled for CRT underwent pre-procedural CT. Reduced LVWT was defined as WT  Results Patients were divided in 3 groups according to the percentage of LVWT  Conclusion WT evaluated using CT could help to stratify the response to CRT and predict MR improvement and outcomes.