Monocyte derived macrophages from lung transplantation patients have an increased M2 profile

I. Schreurs,B. Meek,C.H.M. van Moorsel,D.A. van Kessel, H.D. Luijk,J.C. Grutters

Transplantation Reports（2020）

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摘要

•Monocyte-derived macrophages from lung transplantation patients show an increased frequency of M2a macrophages.•Monocyte-derived macrophages from lung transplantation patients show increased median fluorescence intensity of surface markers.•M2 macrophages are associated with a tissue-regenerated ability possibly leading to development of fibrosis and allograft dysfunction.

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关键词

Lung transplantation,Chronic lung allograft dysfunction,Monocyte-derived macrophages

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