Furosemide And Bumetanide Use And Clinical Outcomes In Extremely Low Birth Weight Infants

Purpose: Extremely low birth weight (ELBW, u003c 1000g) infants are at risk for prolonged assisted ventilation, elevating risk for lung injury, bronchopulmonary dysplasia (BPD) and death. Furosemide and bumetanide are diuretics used to reduce respiratory support. Use of diuretics in ELBW infants is off-label; safety and efficacy is unknown. The objective of this study is to compare the incidence of clinical outcomes in ELBW infants at 2 neonatal intensive care units (NICUs) with different furosemide and bumetanide prescribing …