Gene Editing of Swine Myosin Vb Induces Microvillus Inclusion Disease and Loss of Apical Sodium Transporters with Maintenance of CFTR in Enterocytes

Amy C Engevik, Alex Coutts,Milena Saqui-Salces,Izumi Kaji,Ramya Lekha Medida,Janice Williams,Daniel F Carlson,Tamene Melkamu,James R Goldenring

FASEB JOURNAL（2019）

引用 1|浏览51

暂无评分

摘要

Background The human genetic disorder Microvillus Inclusion Disease (MVID) results from inactivating mutations in Myosin Vb (MYO5B). MVID is characterized by severe, unremitting diarrhea that typic...

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要