Pyrolytic oils from Amphipterygium adstringens bark inhibit IL-8 production of IL-17-stimulated HaCaT keratinocytes

Roberto Esquivel-García,Michael Ayiania,Nehal Abu-Lail,Joel E. López-Meza,Rosa E. del Río,Manuel García-Pérez,Alejandra Ochoa-Zarzosa,Martha-Estrella García-Pérez

Journal of Analytical and Applied Pyrolysis（2020）

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摘要

•Pyrolytic oils from Amphipterygium adstringens bark were obtained by slow pyrolysis.•Phenols were identified to be the dominant compounds identified in pyrolytic oils.•Pyrolytic oils inhibit the IL-8 production of IL-17-stimulated keratinocytes.•Oil-2 showed a similar inhibitory effect on IL-8 production as dexamethasone.•Pyrolytic oils could be explored for treating IL-17 driven dermatological diseases.

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关键词

Amphipterygium adstringens,Slow pyrolysis,IL-8,Phenol,HaCaT,IL-17

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