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Haploid Genetic Screens Identify SPRING/C12ORF49 As a Determinant of SREBP Signaling and Cholesterol Metabolism

Anke Loregger,Matthijs Raaben,Joppe Nieuwenhuis,Josephine M. E. Tan,Lucas T. Jae,Lisa G. van den Hengel,Sebastian Hendrix,Marlene van den Berg,Saskia Scheij,Ji-Ying Song,Ivo J. Huijbers,Lona J. Kroese,Roelof Ottenhoff,Michel van Weeghel,Bart van de Sluis,Thijn Brummelkamp,Noam Zelcer

Nature Communications（2020）

Cited 34|Views80
Key words
CRISPR-Cas9 genome editing,Lipids,Mechanisms of disease,Science,Humanities and Social Sciences,multidisciplinary
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