Cangrelor alleviates bleomycin-induced pulmonary fibrosis by inhibiting platelet activation in mice.

Molecular Immunology(2020)

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摘要
•Cangrelor mitigated lung fibrosis may partly through the inhibition of platelets.•Platelet activtion, neutrophils infiltration and cytokine expression were suppressed by cangrelor treatment in mice.•Cangrelor could be a potential therapeutic drug for pulmonary fibrosis.
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关键词
Pulmonary fibrosis,Cangrelor,Platelets,Neutrophils,Inflammatory cytokines
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