Construction Of Polluted Aerosol In Accumulation That Affects The Incidence Of Lung Cancer

HELIYON(2020)

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摘要
Background: This model demonstrated the correlation between lung cancer incidences and the parts of ambient air pollution according to the National Aeronautics and Space Administration (NASA)'s high resolution technology satellites.Methods: Chemical type of aerosols was investigated by the Aerosol Diagnostics Model such as black carbon, mineral dust, organic carbon, sea-salt and SO4. The model investigated associations between the six year accumulation of each aerosol and lung cancer incidence by Bayesian hierarchical spatio-temporal model. Which also represented integrated geophysical parameters.Results: In analyses of accumulated chemical aerosol component from 2010-2016, the incidence rate ratio (IRR) of patients in 2017 were estimated. We observed a significant increasing risk for organic carbon exposure (IRR 1.021, 95%CI 1.020-1.022), SO4, (IRR 1.026, 95% CI 1.025-1.028) and dust, (IRR 1.061, 95% CI 1.058-1.064). There was also suggestion of an increased risk with, every 1 ug/m(3) increase in organic carbon compound is associated with 21% increased risk of lung cancer, whereas a 26% excess risk of cancer per 1 ug/m(3) increase in mean SO4 and 61% increased risk of lung cancer for dust levels. The other variables were the negative IRR which did not increase the risk of the exposed group.Conclusion: With our results, this process can determine that organic carbon, SO4 and dust was significantly associated with the elevated risk of lung cancer.
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关键词
Lung cancer, Air pollution, Polluted aerosol components, Bayesian model, MERRA-2, Environmental science, Environmental health, Envionmental risk assessment, Environmental toxicology, Public health, Oncology
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