White matter microstructure mediates the association between prenatal exposure to phthalates and behavior problems in preschool children.

Gillian England-Mason,Melody N Grohs,Jess E Reynolds,Amy MacDonald,David Kinniburgh,Jiaying Liu,Jonathan W Martin,Catherine Lebel,Deborah Dewey

Environmental Research（2020）

引用 16|浏览11

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摘要

•Prenatal phthalate exposure may impact preschool brain microstructure.•Phthalates were related to mean diffusivity of several white matter tracts.•Phthalates were related to fractional anisotropy of one white matter tract.•High molecular weight phthalates indirectly predicted preschool behavior problems.

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关键词

Phthalates,Diffusion tensor imaging,White matter microstructure,Preschool children,Behavior problems,APrON study

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