Hepatitis B core-specific memory B cell responses associate with clinical parameters in patients with chronic HBV.

Thomas Vanwolleghem,Zwier M A Groothuismink,Kim Kreefft,Magdeleine Hung,Nikolai Novikov,Andre Boonstra

Journal of Hepatology（2020）

引用 34|浏览14

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摘要

•B cell responses in chronic HBV are predominantly directed against HBcAg, not HBsAg.•HBcAg-specific memory B cells associate with HBV's clinical phases.•HBcAg-specific B cell responses are reduced during antiviral treatment.

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关键词

Hepatitis B core antigen,B cell,Hepatitis B virus,ELISPOT

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