RREB1 Integrates TGF-β and RAS Signals to Drive EMT.

Developmental Cell(2020)

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摘要
TGF-β is long known to require Ras activation to induce EMT. In a recent issue of Nature, Massagué and colleagues (Su et al., 2020) identify RAS-responsive element binding protein 1 (RREB1) as a critical integrator of TGF-β and Ras signals during both developmental and cancer EMT programs.
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