Clinical Features and Outcomes of Bloodstream Infections Caused by New Delhi Metallo-β-Lactamase-Producing Enterobacterales During a Regional Outbreak.

Marco Falcone,Giusy Tiseo,Alberto Antonelli,Cesira Giordano,Vincenzo Di Pilato, Pietro Bertolucci,Eva Maria Parisio,Alessandro Leonildi,Noemi Aiezza,Ilaria Baccani,Enrico Tagliaferri,Lorenzo Righi,Silvia Forni, Spartaco Sani,Maria Teresa Mechi,Filippo Pieralli,Simona Barnini,Gian Maria Rossolini,Francesco Menichetti

OPEN FORUM INFECTIOUS DISEASES（2020）

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摘要

Limited data about New Delhi metallo-beta-lactamase (NDM) bacteremia are available. Blood isolates from 40 patients with NDM bacteremia were studied for antibiotic susceptibility and whole-genomic sequencing. NDM bacteremia has high 30-day mortality. In most cases, aztreonam-avibactam is active in vitro. Ceftazidime-avibactam plus aztreonam may represent a feasible therapeutic option.

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bacteremia,carbapenem-resistant,New Delhi metallo-beta-lactamases

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