Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASG12C.
Jason G. Kettle,Sharan K. Bagal,Sue Bickerton,Michael S. Bodnarchuk,Jason Breed,Rodrigo J. Carbajo,Doyle J. Cassar,Atanu Chakraborty,Sabina Cosulich,Iain Cumming,Michael Davies,Andrew Eatherton,Laura Evans,Lyman Feron,Shaun Fillery,Emma S. Gleave,Frederick W. Goldberg,Stephanie Harlfinger,Lyndsey Hanson,Martin Howard,Rachel Howells,Anne Jackson,Paul Kemmitt, Jennifer K. Kingston,Scott Lamont,Hilary J. Lewis,Songlei Li,Libin Liu,Derek Ogg,Christopher Phillips,Radek Polanski,Graeme Robb,David Robinson,Sarah Ross,James M. Smith,Michael Tonge,Rebecca Whiteley,Junsheng Yang, Longfei Zhang,Xiliang Zhao Journal of medicinal chemistry（2020）
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