Rhodiola crenulata root extract ameliorates fructose-induced hepatic steatosis in rats: Association with activating autophagy.

Chunlin Yuan,Yaqian Jin,Ling Yao,Li Liu,Jinxiu Li,Haifei Li,Ying Lai,Zhiwei Chen,Zheng Pan,TingLi Han,Dazhi Ke,Chunli Li,Shang Wang,Meng Wang,Johji Yamahara,Jianwei Wang

Biomedicine & Pharmacotherapy（2020）

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摘要

•Rhodiola crenulata root ameliorates fructose induced hepatic steatosis.•Rhodiola crenulata root may activate hepatic autophagy in fructose-fed rats.•Rhodiola crenulata root may promote hepatic autophagosome formation and degradation in fructose-fed rats.

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ACC,ACO,AFLD,ATGL,ChREBP,CPT1,DIO,DNL,FAS,FGF21,HFD,HM,HSL,LDs,MGAT,MTTP,NAFLD,PE,PPAR,RCR,SCD,SREBP,SIRT,VLDL

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