Co-Existence of tau and α-synuclein pathology in fetal graft tissue at autopsy: A case report.

Parkinsonism & Related Disorders(2020)

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摘要
•Both a-synuclein and tau pathology in fetal transplanted tissue in a Parkinson's disease patient.•One theory is that α-synuclein and tau pathology spread from host to graft in a neuron-neuron manner.•Alternatively host environment could cause native graft proteins to become phosphorylated.
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关键词
Parkinson's disease,Fetal tissue transplantation,Alpha-synuclein,Tau,Lewy bodies
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