Long-term air pollution exposure is associated with increased severity of rhinitis in 2 European cohorts.
Journal of Allergy and Clinical Immunology(2020)
摘要
A total of 1408 adults with rhinitis (mean age, 52 years; 46% men, 81% from the European Community Respiratory Health Survey) were included. The median (1st quartile-3rd quartile) score of rhinitis severity was 4 (2-6). Higher exposure to PM was associated with higher rhinitis severity (adjusted odds ratio [95% CI] for a 10 μg/m increase in PM: for mild: 1.20 [0.88-1.64], moderate: 1.53 [1.07-2.19], and high severity: 1.72 [1.23-2.41]). Similar results were found for PM. Higher exposure to NO was associated with an increased severity of rhinitis, with similar adjusted odds ratios whatever the level of severity. Adjusted odds ratios were higher among participants without allergic sensitization than among those with, but interaction was found only for NO CONCLUSIONS: People with rhinitis who live in areas with higher levels of pollution are more likely to report more severe nasal symptoms. Further work is required to elucidate the mechanisms of this association.
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关键词
Rhinitis,allergic sensitization,air pollution,environment,severity,respiratory disease
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